Carl Craig has released many successful albums under a large number of aliases, such as BFC, Psyche, Paperclip People, 69, Designer Music and Innerzone Orchestra. He also had a hugely successful collaboration album with NYDJ Patrick Picasso. Using one alias, Innerzone Orchestra, he released perhaps his best-known track "Bug in The Bassbin" in 1992, a track that many regard as being a key influence in the then evolving sound of drum and bass.[citation needed]

Carl Craig has also created his own record label called Planet E Communications, which apart from his own work, has released records by well known techno and house artists like Kevin Saunderson, Alton Miller and Moodymann.

Craig served as co-creator and artistic director for the widely successful Detroit Electronic Music Festival in 2000 and 2001. His subsequent dismissal by festival organizers caused substantial controversy within the Detroit techno community, igniting a high-profile campaign in his favor. In 2001, Craig filed a breach-of-contract lawsuit against festival producer Pop Culture Media. Craig will return as artistic director for the 2010 festival, which is now produced by Paxahau.

Part of what makes Craig's style so unique and separates him from much of the normal "Detroit Techno" sound, including current works, are his remixes of world beat and jazz songs. This has helped spark a new movement of electronic music.[citation needed]

Regarding the many positions he has held in the music industry (artist, producer, DJ, label boss, and more), Craig has said: "I have a bad habit of getting my hands dirty in every little thing, and I really do enjoy it."

He also participated in the collaborations The Detroit Experiment (2002) and Sun Ra Dedication: The Myth Lives on (2003)